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Faculty of Pharmaceutical Sciences: Ron van Schaik, PhD
February 20, 2019 @ 12:00 pm - 1:00 pm
The Faculty of Pharmaceutical Sciences would like to announce the following seminar:
Clinical implementation of Pharmacogenetics: Do YOU have your DNA passport?
Ron van Schaik, PhD
Erasmus Univ. Medical Center
Rotterdam, Netherlands
Wednesday, February 20, 2019 at 12:00 noon
Robert Sindelar Seminar Room 3340
UBC Faculty of Pharmaceutical Sciences
2405 Wesbrook Mall
Adverse drug reactions (ADRs) are responsible for 5-7% of hospitalizations each year. Interindividual variation in drug metabolism is contributing to this problem. DNA analysis of drug metabolizing enzymes can predict the drugs metabolizing capacity of each individual. By simple blood or cheekswab analysis, and drug therapy can be adjusted to personal DNA profile. This will decrease adverse drug reactions and improving effectivity of therapy. Yet, clinical uptake is slow. Our 15 year experience in implementing pharmacogenetics will be illustrated,. Successes as well as unexpected challenges will be addressed. European initiatives such as the European Pharmacogenetics Implementation Consortium (www.eu-pic.net) and the European Society for Pharmacogenomics and Personalized Therapy (ESPT) (www.esptnet.org) will be highlighted.
Erasmus MC provides DNA passports for guiding medication since 2015. With this, one can visit any pharmacy in the Netherlands to obtain medication adjusted to your genomic profile for over 80 drugs. The question is therefore justified: “Do YOU already have your DNA-passport?
