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Department of Microbiology and Immunology: Dr. Vincent B. Young
February 26, 2019 @ 12:30 pm - 1:30 pm
Dr. Vincent B. Young
William Henry Fitzbutler Collegiate Professor
Department of Internal Medicine/Infectious Diseases Department of Microbiology & Immunology
University of Michigan Medical School
Title: “Man, Microbiome and Pathogen: Systems biology of Clostridium difficile infection”
Date: Tuesday, February 26 at 12:30pm in LSC 3
Abstract: The role of the microbiome in human health and disease is the subject of intense research. One of the first conditions for which the microbiome was thought to play a key role is infection with the healthcare-associated bacterial pathogen C. difficile. The recognition of C. difficile infection following antibiotic administration over 40 years ago led to the theory that the indigenous bacteria of the intestine mediated colonization resistance against C. difficile and other pathogens. However, the mechanisms by which this colonization resistance occurred are still incompletely defined. The technical advances in DNA sequencing, bacterial culture and mass spectroscopy that led to the Human Microbiome Project has started to reveal the nature of the complex relationships between the host, the indigenous mcirobiota and pathogens. In this talk I will describe the research that a team of investigators at the University of Michigan is conducting to define the myriad host-microbe interactions in C. difficile infection.
Sponsored by: The Department of Microbiology and Immunology
Hosted by: Dr. Erin Gaynor & Dr. Brett Finlay