MSL Seminar Series: June – Invited Speaker, Dr. Carrie Partch
June 21 @ 3:00 pm - 4:00 pm
Invited Speaker: Dr. Carrie Partch
Professor, Department of Chemistry and Biochemistry – University of California Santa Cruz
This seminar will be presented in a virtual format on Zoom. Please use the zoom registration link below to sign up to attend. We will also be screening the seminar in the MSL lecture theatre (room 102). Feel free to join us in person to watch the virtual seminar.
Zoom registration link:
https://ubc.zoom.us/meeting/register/u5MudemhpjoiGtcLt1Ge7hb1JnuBov5u7ATS
Talk title
An intrinsically disordered phosphoswitch controls circadian timekeeping in humans
Abstract
Our lives are intimately linked to Earth’s 24-hour solar cycle via circadian clocks that coordinate physiology and behavior into rhythms that coincide with the day/night cycle. We are integrating structural biology, biochemistry, and cell biology to identify how dedicated clock proteins interact with one another to establish a deeper understanding of the transcription-based feedback loop that underlies human circadian rhythms. Here, I will discuss how an intrinsically disordered phosphoswitch controls the activity of Casein kinase 1δ to determine the intrinsic timing of circadian clocks in humans.
Hosted by: Dr. Jörg Gsponer